1.
Effect Of Experimentally Induced Coccidiosis On Some Blood Parameters And Its Treatment With Three New Anticoccidial Drugs In Broilers
by Arshad Latif Arshad | Dr. Muhammed Sarwer Khan | Dr. Haji Ahmed | Dr. Muhammad Ashraf | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1995Dissertation note: One hundred and fifty day 01(1 broiler chicks were obtained from a local hatchery. They were reared upto day 26. All the birds were given feed having no coccicliostat.
At the age of 26 clays the birds were divided into five groups A, B, C, D and E. The D and B were control groups. The test groups were infected with 75000 sporulated oocysts On 26th day of age, group D was infected and non medicated while group E was kept non infected and non medicated. The group A, B and C were treated with clopidol, monensin and salinomycin respectively after the appearance of clinical symptoms.
The total oocyst counts in all groups on zero day of infection were nil and on 1st, 5th and 9th day of medication, groups A, B, C, D showed 25800, 20400, 23800, 197500 oocysts counts respectively, while group B examined nil being control non infected group.
The mortalities observed in groups A, B, C, D and E were 6, 2, 3, 8 and nil while percent mortality was 20%, 6.66%, 10%, 26.66% and 0.00%. In treated groups, monensin showed least mortality.
The feed intake and feed conversion of groups A, B and C were almost equal. While group D (infected and non medicated) was relatively poor. As far as group E (non infected and non medicated) is concerned it showed better results.
In haematological studies the average values of haemoglobin levels, erythrocytic count and total serum protein were lower post infection as compared to the respective control group E (non infected and non medicated). The total leukocytic count was increased in all groups as compared to group E (non infected and non medicated). The differential leukocytic count, the lymphocyte decreased, heterophils and monocytes increased. The eosinophils and basophils showed variation in their number.
The study showed efficacy of Monensin, Salinomycin and Clopidol in descending order respectively. Monensin was to be drug of choice against coccidiosis.
Availability: Items available for loan: UVAS Library [Call number: 0428,T] (1).
2.
Extra Articular Substitution Of The Cranial Cruciate Ligament With Patellar Tendon
by Huma Noor | Dr. Mazhar Iqbal | Dr. Mubasher | Dr. Muhammed Younas | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1993Dissertation note: Rupture of the cranial cruciate ligament is the most common cause of hind-limb lameness in the dog. Many techniques have been used for the repair of ruptured cranial cruciate ligament including intra-articular techniques both using synthetic and viable materials.
Viable materials have proved better then synthetic due to lesser chances of rejection and infection. Extra-articular techniques are also though better than intra-articular repairs as whole of the joint is manipulated in the latter which increases the chances of trauma.
In this project 12 dogs were used in which 2 were the control dogs.
The dogs underwent repair of the ruptured cranial cruciate ligament by using extra-articular technique in which a strip of the patellar ligament along with the superficial half of the patella was screwed to the lateral side of the lateral femoral condyle in a way to eliminate the cranial drawer sign. The joint was approached through a medial parapatellar artrotomy. In the control dogs the cranial cruciate ligament was cut but not repaired.
All the dogs were kept in Kennel cages for a period of twelve weeks and evaluated clinically by various physical tests at regular interval. Euthanasia was performed after twelve weeks and the stifle joints of all the operated dogs were explored for gross abnormalities. In case of the repaired dogs, majority of the results confirmed that the joints remained stable throughout the experimental period. However, in case of control dogs the post-euthanasia evaluation was clearly indicative of the complete rupture of cranial cruciate ligaments. Hence it was seen that the surgical technique used in this study provided adequate stability to the stifle joints in which the cranial cruciate ii gament was ruptured experimentally.
Availability: Items available for loan: UVAS Library [Call number: 0431,T] (1).
3.
Comparative Study Of Early And Delayed Skin Autografting On Front Of The Canine Knee
by Azhar Hanif Khatana, M | Dr.Mazhar Iqbal | Dr. Muhammed | Dr. Muhammed Arif Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
; Literary form:
not fiction
Publisher: 1996Dissertation note: Cutaneous injuries particularly when quite massive are burning problems for the working clinicians. Healing in such injuries is unduly prolonged with subsequent granulation and scar formation resulting in uncosmetic look of the skin.
Wounds of the canine knee have plagued both the veterinarian and the owners since long. Most of these wounds fail to respond to conventional methods of treatment. In such cases skin grafting serves as a good alternative for successful covering of the lesions.
The study was done on 20 randomly selected mongrel dogs of either sex. A skin defect starting from 3 cm above and going the same distance down the joint encompassing the medial, cranial and lateral aspects was created and covered with a full thickness skin graft harvested from the lateral aspect of the thigh.
In half of the dogs the grafts were fenestrated whereas in the other half they were kept unfenestrated. In each of the group the right knee was grafted fresh while the left knee underwent delayed grafting when the wounds were uniformly granulating without any clinical signs of infection.
The animals were kept under observation for a period of 21- days. The survival rate of the unfenestrated grafts was 70% (7 out of 10) and 50% (5 out of 10) for the right and left limb respectively whereas in the fenestrated group the success rate was 90% (9 out of 10) in the right limb and 60% (6 out 10) in the left limb. The results indicated that the fenestrated grafts had an edge over the unfenestrated ones whether they were used to cover a fresh or an old granulating wound on the cranial aspect of the canine knee.
Availability: Items available for loan: UVAS Library [Call number: 0491,T] (1).
4.
A Study On Clinico Serilogical Observations By Experimental Aflatoxicosis In Quails
by Mahmood Farooq Qureshi | Dr. Muhammed Athar Khan | Dr. Asif | Dr. Muhammed Sarwer Khan | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1996Dissertation note: In this project the effect of orally administered aflatoxin in feed was observed in quails. Clinicopathological picture was recorded and serum levels in tile liver and intestines of the quails were tested. At the fifth week of age healthy quails in groups A, B, C and D were given feed containing aflatoxin at a rate of 20 PPM, 40 PPM, 60 PPM and zero PPM (control group) respectively. The average (four weeks) mortality rate for groups A, B, C, and D was 21.53%, 44.80%, 54.03% and 0.07% respectively. The average four weeks case fatality rate for group A, B, C and 0 was 82.15%, 90%, 70.33% and 87.50% respectively. The average four weeks aflatoxin level in the intestinal contents was 9.09 PPM, 10.02 PPM, 11.31 PPM and 3.67 PPM in group A, B, C, and 0 respectively. The various levels of aflatoxin in the liver during the four week averaged 0.06 PPM, 5.19 PPM, 16.57 PPM and 0.05 PPM in group A, B, C and O respectively. The various levels of aflatoxin in the serum, were a four week average of 0.11 PPM, 3.69 PPM, 12.44 PPM and zero PPM in group A, B, C, and 0 respectively.
The clinical signs mainifested the birds were ruffled feathers, gathering in the corners of the case, drowsiness, whitish to yellow dilcoloration of eyes, cynchitis, watery discharge from the eyes and nostrils, loose yellowish-white faeces. irregular movement with nervous signs, stiffness of the joints and dehydration.
The necropsy findings were enlarged liver, gastro-entertis and petechial haemorrhages on the amasal ad serosal part of the body, deposition of a yellowish white fluid in the abdominal and thoracic cavity. There wa also pen cardial fluId and asciise in the body.
Availability: Items available for loan: UVAS Library [Call number: 0495,T] (1).
5.
Efficacy Of Different Conjunctival Flaps For Corneal Ulceration In The Dog
by Mubashra Mukadas | Dr. Mazhar Iqbal | Dr. Muhammed Arif Khan | Dr. Shahkeel | Faculty of Veterinary Sciences.
Material type: ; Format:
print
Publisher: 1997Dissertation note: The use of conjunctival flaps is one of the procedures adopted for the repair of cornea in cases of corneal ulceration where the medicinal therapy has limited or no effect. In the begining of the twentieth century many ophthalmic surgeons of human side as well as veterinarians used conjunctiva for the repair of corneal ulcers. They adopted many procedures for this purpose but only a few were found to be successful. These procedures were used to relieve the animal from keratopathies such as infectious keratitis, severely chemically burnt eye, damage of the cornea during accident and progressive deep ulcers. These conditions mostly cause discomfort due to ocular pain and impairment of vision and corneal surgery becomes a necessity.
During this study, fifteen healthy mongrel dogs of either sex were used. These dogs were divided into 5 groups of 3 animals each. The animals of group 1, 2, 3 and 4 were operated upon for the repair of experimentally produced corneal ulcers using conjunctival hood, bridge, complete and pedicle flaps respectively. Group No.5, was kept to serve the purpose of control animals. The cornea was superficially scratched with scalpel blade in all the animals from group No.1 through group No.4 to produce corneal ulcers. The animals were then kept for 15-20 days till corneal ulcers were fully developed. The corneal ulcers thus produced were repaired afterwards, using four different types of conjunctival flaps mentioned earlier.
For preparing conjunctival hood flap, a 1800 incision was made in the bulbar conjunctiva at the limbus and the conjunctiva was superficially dissected towards the fornix. The flap was then pulled centrally and sutured to the sciera with simple interrupted sutures using 6-0 silk. The complete or double hood flaps were prepared by continuing the limbal based conjunctival incision 360° around the limbus. Superficial dissection of the conjunctiva was performed 1-1.5 cm towards the fornices, thus dorsal and ventral flaps were created (by mobilizing the bulbar conjunctiva) and advanced over the cornea to meet centrally. These flaps were apposed with horizontal mattress sutures of 6-0 silk. To prepare bridge or bucket handle flaps, the conjunctiva was first superficially dissected from the limbus and the flap was created via a second incision in the conjunctiva 1-1.5 cm from and parallel to the limbal incision. The flap was then made free and shifted over the corneal ulcer and sutured with simple interrupted sutures using 6-0 silk. The pedicle flaps were dissected and advanced from the limbus and sutured to sciera, covering the corneal ulcers, with simple interrupted sutures of 6-0 silk.
The conjunctival defects were left un-sutured. These procedures were first carried out on the left eyes of all the dogs and then repeated on the right eyes after the healing of left ones.
It was concluded on the basis of this study that:
1. The raw bulbar surface of conjunctiva providing direct access of vascular and fibrous connective tissues can be used, to repair the corneal ulcers.
2. Vision remains almost normal during post operative period without the use of any contact or intra ocular lens.
3. There was no recurrent corneal erosion or penetrating infection, so deeper layers of cornea as well as other intra ocular structures remained normal.
4. Use of topical and/or systemic antibiotics for a long time in the post operative period was not needed.
The successful attempt at repairing the corneal ulcers with the conjunctival flaps strengthened the belief in cases where there was no other way of saving the animal's vision except surgical intervention. So, it is incumbent upon the veterinarian to involve himself devotedly in the operative procedure with the aim of achieving good results. Whether he succeeds or otherwise, he must have a satisfaction of being loyal to his profession.
Availability: Items available for loan: UVAS Library [Call number: 0499,T] (1).
